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In the mix: the potential benefits of adding GM-CSF to CpG-B in the local treatment of patients with early-stage melanoma

Whereas TLR9 agonists are recognized as powerful stimulators of antitumor immunity, GM-CSF has had mixed reviews. In previously reported randomized trials we assessed the effects of local immune modulation in early-stage melanoma with CpG-B alone or with GM-CSF. Here we discuss the added value of GM...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Koster, Bas D., de Jong, Tamarah D., van den Hout, Mari F. C. M., Sluijter, Berbel J. R., Vuylsteke, Ronald J. C. L. M., Molenkamp, Barbara G., Vosslamber, Saskia, van den Tol, M. Petrousjka, van den Eertwegh, Alfons J. M., de Gruijl, Tanja D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959435/
https://ncbi.nlm.nih.gov/pubmed/32002303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1708066
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