Hyaluronan suppresses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-2/8 cells

Cathepsin K is a protease known to be involved in not only bone remodeling and resorption, but also articular cartilage degradation that leads to osteoarthritis (OA). Hyaluronan (HA) plays a pivotal role in maintaining homeostasis within articular chondrocytes. Intra-articular supplementation of hig...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Suzuki, Mochihito, Takahashi, Nobunori, Sobue, Yasumori, Ohashi, Yoshifumi, Kishimoto, Kenji, Hattori, Kyosuke, Ishiguro, Naoki, Kojima, Toshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959248/
https://ncbi.nlm.nih.gov/pubmed/31937805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57073-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados