Platelet HIF-2α promotes thrombogenicity through PAI-1 synthesis and extracellular vesicle release

Oxygen-compromised environments, such as high altitude, are associated with platelet hyperactivity. Platelets confined within the relatively impervious core of an aggregate/thrombus have restricted access to oxygen, yet they continue to perform energy-intensive procoagulant activities that sustain t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Haematologica
Hlavní autoři: Chaurasia, Susheel N., Kushwaha, Geeta, Kulkarni, Paresh P., Mallick, Ram L., Latheef, Nazmy A., Mishra, Jai K., Dash, Debabrata
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959171/
https://ncbi.nlm.nih.gov/pubmed/31004026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.217463
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky