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Effects of cholesterol content on activity of P-glycoproteins and membrane physical state, and consequences for anthelmintic resistance in the nematode Haemonchus contortus

Eukaryote plasma membranes protect cells from chemical attack. Xenobiotics, taken up through passive diffusion, accumulate in the membranes, where they are captured by transporters, among which P-glycoproteins (Pgps). In nematodes such as Haemonchus contortus, eggshells and cuticles provide addition...

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Detalhes bibliográficos
Publicado no:Parasite
Main Authors: Riou, Mickaël, Guégnard, Fabrice, Le Vern, Yves, Grasseau, Isabelle, Koch, Christine, Blesbois, Elisabeth, Kerboeuf, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: EDP Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959138/
https://ncbi.nlm.nih.gov/pubmed/31934848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2019079
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