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Anthelmintics Are Substrates and Activators of Nematode P Glycoprotein
P glycoproteins (Pgp), members of the ABC transporter superfamily, play a major role in chemoresistance. In nematodes, Pgp are responsible for resistance to anthelmintics, suggesting that they are Pgp substrates, as they are in mammalian cells. However, their binding to nematode Pgp and the function...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088189/ https://ncbi.nlm.nih.gov/pubmed/21300828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01477-10 |
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