Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition

Objective: Human carbonyl reductase 1 (CBR1) plays key roles in the regulation of oxidative stress and tumor progression. However, the detailed mechanism and clinical correlation between CBR1 and tumor progression in head and neck squamous cell carcinoma (HNSCC) is largely unexplored. This study wil...

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Pubblicato in:J Cancer
Autori principali: Yun, Miyong, Choi, Ae Jin, Woo, Seon Rang, Noh, Joo Kyung, Sung, Ji-Youn, Lee, Jung-Woo, Eun, Young-Gyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959035/
https://ncbi.nlm.nih.gov/pubmed/31942176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.34303
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