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Inhibition of Carbonyl Reductase 1 Enhances Metastasis of Head and Neck Squamous Cell Carcinoma through β-catenin-Mediated Epithelial-Mesenchymal Transition

Objective: Human carbonyl reductase 1 (CBR1) plays key roles in the regulation of oxidative stress and tumor progression. However, the detailed mechanism and clinical correlation between CBR1 and tumor progression in head and neck squamous cell carcinoma (HNSCC) is largely unexplored. This study wil...

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Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Yun, Miyong, Choi, Ae Jin, Woo, Seon Rang, Noh, Joo Kyung, Sung, Ji-Youn, Lee, Jung-Woo, Eun, Young-Gyu
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959035/
https://ncbi.nlm.nih.gov/pubmed/31942176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.34303
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