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Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles
Studies on the substrate selectivity of recombinant ferrous-iron- and 2-oxoglutarate-dependent proline hydroxylases (PHs) reveal that they can catalyse the production of dihydroxylated 5-, 6-, and 7-membered ring products, and can accept bicyclic substrates. Ring-substituted substrate analogues (suc...
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| Publicado en: | Bioorg Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6958525/ https://ncbi.nlm.nih.gov/pubmed/31706681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2019.103386 |
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