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Bucillamine Prevents Afatinib-Mediated Inhibition of Epidermal Growth Factor Receptor Signaling

Molecular targeting therapies often cause characteristic adverse effects, such as skin rash during anti-epidermal growth factor receptor (EGFR) therapies, making treatment continuation difficult. In contrast, skin symptoms induced by EGFR inhibition are strongly correlated with the overall survival...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Nishiya, Naoyuki, Murai, Moeka, Hosoda, Ayumi, Yonezawa, Honami, Omori, Norikazu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958386/
https://ncbi.nlm.nih.gov/pubmed/31703435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12040165
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