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Next-generation proteasome inhibitor oprozomib enhances sensitivity to doxorubicin in triple-negative breast cancer cells

Doxorubicin (DOX) is the most common chemotherapeutic drug for treatment of breast cancer but intrinsic and acquired resistance frequently occurs and severe side effects occur at high doses. DOX might induce activation of NF-κB causing this resistance, in which case proteasome inhibitors could inhib...

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Podrobná bibliografie
Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Shi, Yonghua, Bieerkehazhi, Shayahati, Ma, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958235/
https://ncbi.nlm.nih.gov/pubmed/31938346
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