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Next-generation proteasome inhibitor oprozomib enhances sensitivity to doxorubicin in triple-negative breast cancer cells

Doxorubicin (DOX) is the most common chemotherapeutic drug for treatment of breast cancer but intrinsic and acquired resistance frequently occurs and severe side effects occur at high doses. DOX might induce activation of NF-κB causing this resistance, in which case proteasome inhibitors could inhib...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Shi, Yonghua, Bieerkehazhi, Shayahati, Ma, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958235/
https://ncbi.nlm.nih.gov/pubmed/31938346
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