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Next-generation proteasome inhibitor oprozomib enhances sensitivity to doxorubicin in triple-negative breast cancer cells

Doxorubicin (DOX) is the most common chemotherapeutic drug for treatment of breast cancer but intrinsic and acquired resistance frequently occurs and severe side effects occur at high doses. DOX might induce activation of NF-κB causing this resistance, in which case proteasome inhibitors could inhib...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Pathol
Main Authors: Shi, Yonghua, Bieerkehazhi, Shayahati, Ma, Hong
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958235/
https://ncbi.nlm.nih.gov/pubmed/31938346
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