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Profilin-1 mediates microvascular endothelial dysfunction in diabetic retinopathy through HIF-1α-dependent pathway

Background: Diabetic retinopathy (DR), a well-known serious complication of diabetes mellitus, can eventually advance to end-stage blindness. Aim: To investigate the role of profilin-1 (PFN1) in microvascular endothelial dysfunction (MVED) triggered by DR. Methods: We assessed the expression of PFN1...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Ding, Hao, Chen, Bin, Lu, Qianyi, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958150/
https://ncbi.nlm.nih.gov/pubmed/31938219
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