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The putative tumour suppressor microRNA-145, repressed by c-jun, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1

Aberrant expression of miR-145 has frequently been reported in cancer studies; however, its role in renal cell carcinoma (RCC) has not been examined in detail. Here, we showed that miR-145 was downregulated in RCC cells and tissues and associated with a poor prognostic phenotype in RCC patients. Res...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Ding, Zhen, Zhang, Xiao, Qiao, Zhu, Li, Hui, Ma, Qi, Liu, Xiaowei, Ding, Shangwei
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957973/
https://ncbi.nlm.nih.gov/pubmed/31938095
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