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Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer

Ferroptosis is a new form of regulated cell death driven by iron-dependent lipid peroxidation. Glutaminolysis and tricarboxylic acid cycle are involved in ferroptosis, but the underlying metabolic process remains unclear. We examined the role of dihydrolipoamide dehydrogenase (DLD) in ferroptosis in...

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Publicado en:Redox Biol
Main Authors: Shin, Daiha, Lee, Jaewang, You, Ji Hyeon, Kim, Doyeon, Roh, Jong-Lyel
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957841/
https://ncbi.nlm.nih.gov/pubmed/31931284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101418
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