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Off-DNA DNA-Encoded Library Affinity Screening

DNA-encoded library (DEL) technology is emerging as a key element of the small molecule discovery toolbox. Conventional DEL screens (i.e., on-DNA screening) interrogate large combinatorial libraries via affinity selection of DNA-tagged library members that are ligands of a purified and immobilized p...

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Bibliografiske detaljer
Udgivet i:ACS Comb Sci
Main Authors: Hackler, Amber L., FitzGerald, Forrest G., Dang, Vuong Q., Satz, Alexander L., Paegel, Brian M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957756/
https://ncbi.nlm.nih.gov/pubmed/31829554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.9b00153
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