Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity

Microfold cells (M cells) are responsible for antigen uptake to initiate immune responses in the gut-associated lymphoid tissue (GALT). Receptor activator of nuclear factor-κB ligand (RANKL) is essential for M cell differentiation. Follicle-associated epithelium (FAE) covers the GALT and is continuo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kimura, Shunsuke, Nakamura, Yutaka, Kobayashi, Nobuhide, Shiroguchi, Katsuyuki, Kawakami, Eiryo, Mutoh, Mami, Takahashi-Iwanaga, Hiromi, Yamada, Takahiro, Hisamoto, Meri, Nakamura, Midori, Udagawa, Nobuyuki, Sato, Shintaro, Kaisho, Tsuneyasu, Iwanaga, Toshihiko, Hase, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957684/
https://ncbi.nlm.nih.gov/pubmed/31932605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13883-y
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