Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice

Microfold (M) cells residing in the follicle-associated epithelium (FAE) of the gut-associated lymphoid tissue are specialized for antigen uptake to initiate mucosal immune responses. The molecular machinery and biological significance of M cell differentiation, however, remain to be fully elucidate...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Kimura, Shunsuke, Kobayashi, Nobuhide, Nakamura, Yutaka, Kanaya, Takashi, Takahashi, Daisuke, Fujiki, Ryoji, Mutoh, Mami, Obata, Yuuki, Iwanaga, Toshihiko, Nakagawa, Tomoo, Kato, Naoya, Sato, Shintaro, Kaisho, Tsuneyasu, Ohno, Hiroshi, Hase, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446867/
https://ncbi.nlm.nih.gov/pubmed/30877171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181604
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