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High level MYC amplification in B-cell lymphomas: is it a marker of aggressive disease?

While MYC translocations in B-cell lymphoma (BCL) have been extensively studied, the significance of MYC amplification (MYC amp) is poorly understood. This study characterizes BCL showing MYC amp, defined as uncountable FISH signals. Retrospective analysis of all BCL FISH for MYC aberrations perform...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Pophali, Priyanka A., Marinelli, Lisa M., Ketterling, Rhett P., Meyer, Reid G., McPhail, Ellen D., Kurtin, Paul J., Mwangi, Raphael, Maurer, Matthew J., Habermann, Thomas, King, Rebecca L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957498/
https://ncbi.nlm.nih.gov/pubmed/31932576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0271-z
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