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AMPK inhibits myoblast differentiation through a PGC-1α-dependent mechanism

Elevated phosphorylation of AMP-activated protein kinase (AMPK) has been shown to inhibit skeletal muscle growth in both culture and animal models, but its role in differentiation of muscle cells is less clear. p21 is known to have an important role in differentiation, but AMPK's role regulatin...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Williamson, David L., Butler, David C., Alway, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957363/
https://ncbi.nlm.nih.gov/pubmed/19491292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.91007.2008
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