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Phospho-Ablated Id2 Is Growth Suppressive and Pro-Apoptotic in Proliferating Myoblasts

Inhibitor of differentiation protein-2 (Id2) is a dominant negative helix-loop-helix (HLH) protein, and a positive regulator of proliferation, in various cells. The N-terminal region of Id2 contains a consensus cdk2 phosphorylation sequence SPVR, which may be involved with the induction of apoptosis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Butler, David C., Haramizu, Satoshi, Williamson, David L., Alway, Stephen E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706990/
https://ncbi.nlm.nih.gov/pubmed/19609365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006302
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