SKA-31, an activator of Ca(2+)-activated K(+) channels, improves cardiovascular function in aging

Aging represents an independent risk factor for the development of cardiovascular disease, and is associated with complex structural and functional alterations in the vasculature, such as endothelial dysfunction. Small- and intermediate-conductance, Ca(2+)-activated K(+) channels (KCa2.3 and KCa3.1,...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: John, Cini Mathew, Mallat, Rayan Khaddaj, Mishra, Ramesh C, George, Grace, Singh, Vikrant, Turnbull, Jeannine D, Umeshappa, Channakeshava S, Kendrick, Dylan J, Kim, Taeyeob, Fauzi, Fazlin M, Visser, Frank, Fedak, Paul WM, Wulff, Heike, Braun, Andrew P
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956598/
https://ncbi.nlm.nih.gov/pubmed/31707036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2019.104539
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