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Pharmacological Targeting of KCa Channels to Improve Endothelial Function in the Spontaneously Hypertensive Rat

Systemic hypertension is a major risk factor for the development of cardiovascular disease and is often associated with endothelial dysfunction. KCa2.3 and KCa3.1 channels are expressed in the vascular endothelium and contribute to stimulus-evoked vasodilation. We hypothesized that acute treatment w...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Khaddaj Mallat, Rayan, Mathew John, Cini, Mishra, Ramesh C, Kendrick, Dylan J, Braun, Andrew P
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678254/
https://ncbi.nlm.nih.gov/pubmed/31315169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143481
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