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Urokinase-type plasminogen activator (uPA) regulates the expression and function of growth-associated protein 43 (GAP-43) in the synapse

Growth-associated protein 43 (GAP-43) plays a central role in the formation of presynaptic terminals, synaptic plasticity, and axonal growth and regeneration. During development, GAP-43 is found in axonal extensions of most neurons. In contrast, in the mature brain, its expression is restricted to a...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Merino, Paola, Diaz, Ariel, Torre, Enrique R., Yepes, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956544/
https://ncbi.nlm.nih.gov/pubmed/31819012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010644
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