Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis

AIMS: Adequate plasma concentrations of antibiotics during surgery are essential for the prevention of surgical site infections. We examined the pharmacokinetics of 1.5 g cefuroxime administered during induction of anaesthesia with follow‐up doses every 2.5 hours until the end of surgery. We built a...

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Bibliografische gegevens
Gepubliceerd in:Br J Clin Pharmacol
Hoofdauteurs: Rimmler, Christer, Lanckohr, Christian, Akamp, Ceren, Horn, Dagmar, Fobker, Manfred, Wiebe, Karsten, Redwan, Bassam, Ellger, Bjoern, Koeck, Robin, Hempel, Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955413/
https://ncbi.nlm.nih.gov/pubmed/31487057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14121
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