Determinants governing T cell receptor α/β-chain pairing in repertoire formation of identical twins

The T cell repertoire in each individual includes T cell receptors (TCRs) of enormous sequence diversity through the pairing of diverse TCR α- and β-chains, each generated by somatic recombination of paralogous gene segments. Whether the TCR repertoire contributes to susceptibility to infectious or...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tanno, Hidetaka, Gould, Timothy M., McDaniel, Jonathan R., Cao, Wenqiang, Tanno, Yuri, Durrett, Russell E., Park, Daechan, Cate, Steven J., Hildebrand, William H., Dekker, Cornelia L., Tian, Lu, Weyand, Cornelia M., Georgiou, George, Goronzy, Jörg J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955297/
https://ncbi.nlm.nih.gov/pubmed/31879353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915008117
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