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DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products

Microbial natural products represent a rich resource of evolved chemistry that forms the basis for the majority of pharmacotherapeutics. Ribosomally synthesized and posttranslationally modified peptides (RiPPs) are a particularly interesting class of natural products noted for their unique mode of b...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Merwin, Nishanth J., Mousa, Walaa K., Dejong, Chris A., Skinnider, Michael A., Cannon, Michael J., Li, Haoxin, Dial, Keshav, Gunabalasingam, Mathusan, Johnston, Chad, Magarvey, Nathan A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955231/
https://ncbi.nlm.nih.gov/pubmed/31871149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901493116
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