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Hydrophobic residues of melittin mediate its binding to αA−crystallin

The molecular chaperone αA‐crystallin, mainly localized in the human ocular lens, is believed to protect the lens from opacification and cataract, by suppressing the aggregation of the other lens proteins. The present study provides structural and thermodynamic insights into the ability of human αA‐...

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Dettagli Bibliografici
Pubblicato in:Protein Sci
Autori principali: Ramirez, Lisa M., Shekhtman, Alexander, Pande, Jayanti
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954717/
https://ncbi.nlm.nih.gov/pubmed/31762096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3792
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