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Building better enzymes: Molecular basis of improved non‐natural nucleobase incorporation by an evolved DNA polymerase
Obtaining semisynthetic microorganisms that exploit the information density of “hachimoji” DNA requires access to engineered DNA polymerases. A KlenTaq variant has been reported that incorporates the “hachimoji” P:Z nucleobase pair with a similar efficiency to that seen for Watson–Crick nucleobase i...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6954703/ https://ncbi.nlm.nih.gov/pubmed/31654473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3762 |
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