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Should we be more cre‐tical? A cautionary tale of recombination

The cre‐loxP system has been revolutionary in the field of immunology. The technology enables genetic deletion in mice with unprecedented precision. It is therefore now widely used to investigate gene functions in animal models of disease, and in fundamental studies of the immune response. This wide...

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Pubblicato in:Immunology
Autori principali: Andrusaite, Anna, Milling, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954702/
https://ncbi.nlm.nih.gov/pubmed/31926027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13170
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