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Should we be more cre‐tical? A cautionary tale of recombination

The cre‐loxP system has been revolutionary in the field of immunology. The technology enables genetic deletion in mice with unprecedented precision. It is therefore now widely used to investigate gene functions in animal models of disease, and in fundamental studies of the immune response. This wide...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Andrusaite, Anna, Milling, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954702/
https://ncbi.nlm.nih.gov/pubmed/31926027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13170
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