Preclinical Evaluation of (203/212)Pb-Labeled Low-Molecular-Weight Compounds for Targeted Radiopharmaceutical Therapy of Prostate Cancer

Targeted radiopharmaceutical therapy (TRT) using α-particle radiation is a promising approach for treating both large and micrometastatic lesions. We developed prostate-specific membrane antigen (PSMA)–targeted low-molecular-weight agents for (212)Pb-based TRT of patients with prostate cancer (PC) b...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Banerjee, Sangeeta Ray, Minn, Il, Kumar, Vivek, Josefsson, Anders, Lisok, Ala, Brummet, Mary, Chen, Jian, Kiess, Ana P., Baidoo, Kwamena, Brayton, Cory, Mease, Ronnie C., Brechbiel, Martin, Sgouros, George, Hobbs, Robert F., Pomper, Martin G.
Format: Artigo
Language:Inglês
Published: Society of Nuclear Medicine 2020
Subjects:
Theranostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954458/
https://ncbi.nlm.nih.gov/pubmed/31253744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.229393
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