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Same fold, different properties: polarizable molecular dynamics simulations of telomeric and TERRA G-quadruplexes

DNA and RNA sequences rich in guanine can fold into noncanonical structures called G-quadruplexes (GQs), which exhibit a common stem structure of Hoogsteen hydrogen-bonded guanine tetrads and diverse loop structures. GQ sequence motifs are overrepresented in promoters, origins of replication, telome...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Autor principal: Lemkul, Justin A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954416/
https://ncbi.nlm.nih.gov/pubmed/31807754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1154
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