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Ion Binding Properties and Dynamics of the bcl-2 G-Quadruplex Using a Polarizable Force Field

G-quadruplexes (GQs) are topologically diverse, highly thermostable noncanonical nucleic acid structures that form in guanine-rich sequences in DNA and RNA. GQs are implicated in transcriptional and translational regulation and genome maintenance, and deleterious alterations to their structures cont...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Ratnasinghe, Brian D., Salsbury, Alexa M., Lemkul, Justin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775346/
https://ncbi.nlm.nih.gov/pubmed/33264004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c01064
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