Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

Around 40% of preterm births are attributed to ascending intrauterine infection, and Ureaplasma parvum (UP) is commonly isolated in these cases. Here we present a mouse model of ascending UP infection that resembles human disease, using vaginal inoculation combined with mild cervical injury induced...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pavlidis, Ioannis, Spiller, Owen B., Sammut Demarco, Gabriella, MacPherson, Heather, Howie, Sarah E. M., Norman, Jane E., Stock, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954262/
https://ncbi.nlm.nih.gov/pubmed/31924800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14089-y
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