Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells

Efficient generation of human induced pluripotent stem cell (hiPSC)-derived human intestinal organoids (HIOs) would facilitate the development of in vitro models for a variety of diseases that affect the gastrointestinal tract, such as inflammatory bowel disease or Cystic Fibrosis. Here, we report a...

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Udgivet i:Nat Commun
Main Authors: Mithal, Aditya, Capilla, Amalia, Heinze, Dar, Berical, Andrew, Villacorta-Martin, Carlos, Vedaie, Marall, Jacob, Anjali, Abo, Kristine, Szymaniak, Aleksander, Peasley, Megan, Stuffer, Alexander, Mahoney, John, Kotton, Darrell N., Hawkins, Finn, Mostoslavsky, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954238/
https://ncbi.nlm.nih.gov/pubmed/31924806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13916-6
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