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Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Challenges in drug development of neurological diseases remain mainly ascribed to the blood–brain barrier (BBB). Despite the valuable contribution of animal models to drug discovery, it remains difficult to conduct mechanistic studies on the barrier function and interactions with drugs at molecular...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ahn, Song Ih, Sei, Yoshitaka J., Park, Hyun-Ji, Kim, Jinhwan, Ryu, Yujung, Choi, Jeongmoon J., Sung, Hak-Joon, MacDonald, Tobey J., Levey, Allan I., Kim, YongTae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954233/
https://ncbi.nlm.nih.gov/pubmed/31924752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13896-7
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