Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Challenges in drug development of neurological diseases remain mainly ascribed to the blood–brain barrier (BBB). Despite the valuable contribution of animal models to drug discovery, it remains difficult to conduct mechanistic studies on the barrier function and interactions with drugs at molecular...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Ahn, Song Ih, Sei, Yoshitaka J., Park, Hyun-Ji, Kim, Jinhwan, Ryu, Yujung, Choi, Jeongmoon J., Sung, Hak-Joon, MacDonald, Tobey J., Levey, Allan I., Kim, YongTae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954233/
https://ncbi.nlm.nih.gov/pubmed/31924752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13896-7
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