Loss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis

Accelerated atherosclerotic calcification is responsible for plaque burden, especially in diabetes. The regulatory mechanism for atherosclerotic calcification in diabetes is poorly characterized. Here we show that deletion of PARP-1, a main enzyme in diverse metabolic complications, attenuates diabe...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Li, Peng, Wang, Ying, Liu, Xue, Liu, Bin, Wang, Zhao-yang, Xie, Fei, Qiao, Wen, Liang, Er-shun, Lu, Qing-hua, Zhang, Ming-xiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954221/
https://ncbi.nlm.nih.gov/pubmed/31924749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2215-8
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