Loss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis

Accelerated atherosclerotic calcification is responsible for plaque burden, especially in diabetes. The regulatory mechanism for atherosclerotic calcification in diabetes is poorly characterized. Here we show that deletion of PARP-1, a main enzyme in diverse metabolic complications, attenuates diabe...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Peng, Wang, Ying, Liu, Xue, Liu, Bin, Wang, Zhao-yang, Xie, Fei, Qiao, Wen, Liang, Er-shun, Lu, Qing-hua, Zhang, Ming-xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954221/
https://ncbi.nlm.nih.gov/pubmed/31924749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2215-8
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