Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study

PURPOSE: Increased systemic cortisol availability during adult critical illness is determined by reduced binding-proteins and suppressed breakdown rather than elevated ACTH. Dynamics, drivers and prognostic value of hypercortisolism during pediatric critical illness remain scarcely investigated. MET...

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Dades bibliogràfiques
Publicat a:Intensive Care Med
Autors principals: Jacobs, An, Derese, Inge, Vander Perre, Sarah, Wouters, Pieter J., Verbruggen, Sascha, Billen, Jaak, Vermeersch, Pieter, Garcia Guerra, Gonzalo, Joosten, Koen, Vanhorebeek, Ilse, Van den Berghe, Greet
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Pediatric Original
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954148/
https://ncbi.nlm.nih.gov/pubmed/31713058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-019-05854-0
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