Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU

BACKGROUND: A genome-wide study identified de novo DNA methylation alterations in leukocytes of children at paediatric intensive care unit (PICU) discharge, offering a biological basis for their impaired long-term development. Early parenteral nutrition (early-PN) in PICU, compared with omitting PN...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Verlinden, Ines, Güiza, Fabian, Derese, Inge, Wouters, Pieter J., Joosten, Koen, Verbruggen, Sascha C., Van den Berghe, Greet, Vanhorebeek, Ilse
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576729/
https://ncbi.nlm.nih.gov/pubmed/33081814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00947-w
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