The RNA-binding protein HuR is a negative regulator in adipogenesis

Human antigen R (HuR) is an essential regulator of RNA metabolism, but its function in metabolism remains unclear. This study identifies HuR as a major repressor during adipogenesis. Knockdown and overexpression of HuR in primary adipocyte culture enhances and inhibits adipogenesis in vitro, respect...

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發表在:Nat Commun
Main Authors: Siang, Diana Teh Chee, Lim, Yen Ching, Kyaw, Aung Maung Maung, Win, Khaing Nwe, Chia, Sook Yoong, Degirmenci, Ufuk, Hu, Xiang, Tan, Bryan C., Walet, Arcinas Camille Esther, Sun, Lei, Xu, Dan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954112/
https://ncbi.nlm.nih.gov/pubmed/31924774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14001-8
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