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Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping
Polycomb repressive complexes 1 and 2 have been historically described as transcriptional repressors, but recent reports suggest that PRC1 might also support activation, although the underlying mechanisms remain elusive. Here, we show that stage-specific PRC1 binding at a subset of active promoters...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6954061/ https://ncbi.nlm.nih.gov/pubmed/31950077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax4001 |
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