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Neutrophils Deficient in Innate Suppressor IRAK-M Enhances Anti-tumor Immune Responses

Tumor-associated immune-suppressive neutrophils are prevalent in various cancers, including colorectal cancer. However, mechanisms of immune-suppressive neutrophils are not well understood. We report that a key innate suppressor, IRAK-M (interleukin-1 receptor-associated kinase M), is critically inv...

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Foilsithe in:Mol Ther
Main Authors: Zhang, Yao, Diao, Na, Lee, Christina K., Chu, Hong Wei, Bai, Lan, Li, Liwu
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953792/
https://ncbi.nlm.nih.gov/pubmed/31607540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.09.019
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