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Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth
IRAK-M is a negative regulator of innate immunity signaling processes. Although attenuation of innate immunity may help to prevent excessive inflammation, it may also lead to compromised immune surveillance of tumor cells and contribute to tumor formation and growth. Here, we demonstrate that IRAK-M...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956318/ https://ncbi.nlm.nih.gov/pubmed/17477969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.03.018 |
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