Erythromyeloid progenitors give rise to a population of osteoclasts contributing to bone homeostasis and repair

The osteoclast is a multinucleated monocyte/macrophage lineage cell that degrades bone. Here we used lineage tracing studies, labeling cells expressing Cx3cr1, Csf1r, or Flt3 to identify the precursors of osteoclast in mice. We identified an erythromyeloid progenitor (EMP)-derived osteoclast precurs...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Yahara, Yasuhito, Barrientos, Tomasa, Tang, Yuning J., Puviindran, Vijitha, Nadesan, Puviindran, Zhang, Hongyuan, Gibson, Jason, Gregory, Simon G., Diao, Yarui, Xiang, Yu, Qadri, Yawar J., Souma, Tomokazu, Shinohara, Mari L., Alman, Benjamin A.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953622/
https://ncbi.nlm.nih.gov/pubmed/31907410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0437-8
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