P53, Somatostatin receptor 2a and Chromogranin A immunostaining as prognostic markers in high grade gastroenteropancreatic neuroendocrine neoplasms

BACKGROUND: High grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) with a Ki67 proliferation index > 20%, include well-differentiated tumours grade 3 (NET G3) and poorly differentiated (PD) neuroendocrine carcinomas (NEC). Abnormal p53-expression is a feature of PD tumours, while...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Nielsen, Kirstine, Binderup, Tina, Langer, Seppo W., Kjaer, Andreas, Knigge, Pauline, Grøndahl, Veronica, Melchior, Linea, Federspiel, Birgitte, Knigge, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953213/
https://ncbi.nlm.nih.gov/pubmed/31924180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6498-z
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