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Inverse expression of somatostatin and CXCR4 chemokine receptors in gastroenteropancreatic neuroendocrine neoplasms of different malignancy

INTRODUCTION: Somatostatin receptors (SSTR) are widely distributed in well-differentiated neuroendocrine neoplasms (NEN) and serve as primary targets for diagnostics and treatment. An overexpression of the chemokine receptor CXCR4, in contrast, is considered to be present mainly in highly proliferat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kaemmerer, Daniel, Träger, Tina, Hoffmeister, Maike, Sipos, Bence, Hommann, Merten, Sänger, Järg, Schulz, Stefan, Lupp, Amelie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695009/
https://ncbi.nlm.nih.gov/pubmed/26259237
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