Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer’s Disease

Dysregulation of the Endoplasmic Reticulum (ER) Ca(2+) homeostasis and subsequent ER stress activation occur in Alzheimer Disease (AD). We studied the contribution of the human truncated isoform of the sarco-endoplasmic reticulum Ca(2+) ATPase 1 (S1T) to AD. We examined S1T expression in human AD-af...

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Gepubliceerd in:Cells
Hoofdauteurs: Bussiere, Renaud, Oulès, Bénédicte, Mary, Arnaud, Vaillant-Beuchot, Loan, Martin, Cécile, El Manaa, Wejdane, Vallée, Déborah, Duplan, Eric, Paterlini-Bréchot, Patrizia, Alves Da Costa, Cristine, Checler, Frédéric, Chami, Mounia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953121/
https://ncbi.nlm.nih.gov/pubmed/31795302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121539
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