Serca1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis

By pumping calcium from the cytosol to the ER, sarco/endoplasmic reticulum calcium ATPases (SERCAs) play a major role in the control of calcium signaling. We describe two SERCA1 splice variants (S1Ts) characterized by exon 4 and/or exon 11 splicing, encoding COOH terminally truncated proteins, havin...

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Autori principali: Chami, Mounia, Gozuacik, Devrim, Lagorce, David, Brini, Marisa, Falson, Pierre, Peaucellier, Gérard, Pinton, Paolo, Lecoeur, Hervé, Gougeon, Marie-Lyse, le Maire, Marc, Rizzuto, Rosario, Bréchot, Christian, Paterlini-Bréchot, Patrizia
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192035/
https://ncbi.nlm.nih.gov/pubmed/11402072
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